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新型光活化抗菌涂层

发布时间:2020.06.17    点击数: 60513

      由伦敦大学学院(UCL)组成的研发团队近期开发了一种新型涂层,该涂层可以在低强度的光照条件下激活杀菌活性,从而杀灭金黄色葡萄球菌和大肠杆菌等细菌。该涂层适用于手机屏、键盘、导管及呼吸管内壁等,起到抑制疾病传播扩撒的作用。

低强度光下具有抗菌活性的涂层

该研究项目首次推出了一种低强度光条件下具有活性的抗菌涂层,如在病房和候诊室等低强度光(300 lux)环境下,该涂层能有效杀灭细菌。之前的研究成果只能将涂层在诸如手术室那样使用强光(3,000 lux)的环境下才能激活涂层的抗菌活性。


最常见的传染病是由艰难梭菌(C. difficile)、耐甲氧西林的金黄色葡萄球菌(MRSA)和大肠杆菌(E. coli)等菌种引起的。这类疾病通常发生在住院期间或外科手术治疗期间,也会在就诊时发生,对健康构成严重威胁,英国国家医疗服务体系(NHS)对此很重视。

项目成员Gi Byoung Hwang博士认为,“结晶紫染料广泛用于伤口消毒处理,以此杀灭细菌并保持医疗器械表面无菌。当暴露在强光下时,结晶紫会产生活性氧,进而通过破坏细菌的保护膜和DNA来达到杀灭的目的。如果将其与银,金和氧化锌等金属配伍时,抗菌性能会更出色。” 

UCL化学所Ivan Parkin教授认为,“其他涂层只有在暴露于对人体有害的紫外线或强光源下才能有效杀灭细菌。而QY千亿国际研发的涂层即使在环境光下也能有效杀死金黄色葡萄球菌和大肠杆菌,使其有望在各种医疗领域推广使用。”

抗菌性能测试

研究团队采用了梯度分析法来测试不同光照条件下涂层对金黄色葡萄球菌和大肠杆菌的杀灭效果。

先制备了抗菌涂层试样和对比涂层试样,然后试样表面滴入100,000 CFU/mL金黄色葡萄球菌和大肠杆菌,并在200~429 lux强度环境光条件下研究了细菌的生长情况。

研究发现,在上述环境光条件下,对比涂层试样没有杀死任何一种细菌。但抗菌涂层试样导致6 h后金黄色葡萄球菌的生长减少了3.3 log,24 h后大肠杆菌的生长减少了2.8 log。

UCL伊士曼牙科研究院Elaine Allan博士表示,“大肠杆菌对抗菌涂层的耐受性比金黄色葡萄球菌强,这是因为大肠杆菌的细胞壁具有双膜结构,而金黄色葡萄球菌仅具有单个膜屏障。”

研究小组还发现,该抗菌涂层通过产生过氧化氢来杀死细菌。过氧化氢是一种用于隐形眼镜清洁剂溶液的相对温和的试剂。它通过化学攻击细胞膜起作用,因此需要更长的时间才能对具有更多保护膜结构的细菌起到杀灭作用。

该研究获得了英国工程和自然科学研究委员会“医用材料先进流体制造技术”项目资助。

来源:涂料工业

        关于QY千亿国际智能 About Liangshi InteRobot:
        上海QY千亿国际智能科技股份有限公司(股票代码:837430 厚积薄发 持续创新),为全球客户提供智能制造和表面处理系统解决方案,从业30多年,是一个集研发、设计、制造、工程安装、工程咨询于一体的专业化制造及自动化智能控制系统集成公司,能为客户解决:
        Shanghai Liangshi InteRobot Technology Corporation (Stock Code: 837430 Accumulate richly and break forth vastly; innovate continuously) provides surface treatment sandblasting system solution for global customers. By engaging in this industry for more than twenty years, we're a professional manufacturing and automatic intelligent control system corporation, which integrates researching, designing, manufacturing, project installation and project consulting. We can provide our customers with:
        1、化学表面处理喷抛丸、喷丸强化设备、热喷涂和涂装设备工艺系统解决方案和工艺装备;
              We provide process system solution and process equipments of surface treatment sandblasting shot blasting, shot peening, enameling, thermal spraying, coating equipment.
        2、智能制造自动化机器人应用工艺系统解决方案和工艺装备;
              We provide professional system solution and process equipments of automation and robot technology application.
        3、食品乳品、制药、生物、制冷、石油化工、船舶制造、能源、造纸、纺织系统领域承压系统集成整体解决方案;
              We provide professional integrated solution for pressure bearing system in fields of food dairy, biopharmaceutical, refrigerating, petrochemical, marine engineering, energy, paper-making, fabrics, etc.
        4、涂装环保设备:VOC废气、废水、粉尘处理和噪音治理系统工艺解决方案和工艺装备。
              We provide environment protection blasting and painting equipment: process solution and equipment of VOCs waste gas, waste water, dust, noise treatment system.
         5、专业提供压力容器设计制造:为食品乳品、生物制药、水处理、制冷、石油化工、船舶海工、电力能源、造纸纺织、有色金属等领域提供承压系统集成整体解决方案。
              Professionally provide the design and manufacture of pressure vessels: providing overall solutions for pressure system integration in the fields of food and dairy, biopharmaceutical, water treatment, refrigeration, petrochemical, shipbuilding and marine engineering, power and energy, paper and textile, non-ferrous metals and other fields.
        企业主导产品如下 The leading products of our company are as follows:
        主营业务:智能制造和表面处理工程系统集成的设计、研发、生产和销售。
        Main business: design, research, production and sales of surface treatment engineering system integration.
        六类主要产品:自动化涂装生产线、智能机器人喷涂系统、自动化喷抛丸生产线、智能机器人喷抛丸强化系统、自动化热喷涂系统、涂装节能环保设备。
        Six main product categories are: automatic painting production line, intelligent robot painting system, automatic shot/wheel blasting production line, intelligent robot shot peening system, automatic thermal spraying system, energy saving and environmental protection equipment for painting.
        产品主要应用于:新材料、新能源、工程机械、汽车制造、集装箱、船舶海洋工程、航空航天、港口桥梁、电子电气、环保工程、印刷造纸机械、医疗机械、纺织机械等领域。
        The products are mainly applied in: new materials, new energy, engineering machinery, automobile manufacturing, containers, marine engineering, aeronautics and astronautics, port bridges, electronic and electrical, environmental protection engineering, printing and papermaking machinery, medical machinery, textile machinery and so on.
        公司生产的表面工程系统集成具备智能、自动化的特点,可实现工业生产过程自动化控制,因而属于自动化装备。根据《高端装备制造业“十二五”规划》中对高端装备的定义“主要包括传统产业转型升级和战略性新兴产业发展所需的高技术高附加值装备”,公司产品属于高端装备,是为国民经济其他行业提供技术装备的战略性产业。
        The surface engineering system of our company integrates the characteristics of intelligence and automation, it can realize the automatic control of industrial production process, so it belongs to automatic equipment. According to the definition of premium-end equipment of 《The 125th programme of premium-end equipment manufacturing industry》, “it mainly includes the high technology and high value-added equipment required by traditional industrial transformation upgrading and the development of strategic new-emerging industries”. The company's products belong to the premium-end equipment, which is a strategic industry that provides technical equipment for the other industries of the national economy.
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